Testa Analytical Solutions e.K. has introduced a Surface Zeta Potential option for its NanoBrook range of zeta potential analysers.
Adding the new surface zeta potential option to a Nanobrook analyser allows you to measure the electrical charge on materials like coated glass, plastic, tape, or other flexible surfaces. The system uses known probe particles and purpose-designed electrode to calculate surface zeta potential.

Brookhaven's NanoBrook Omni instrument combines the best technology from our particle/protein sizer and zeta potential analyzer in to one powerful and accurate solution for sizing and zeta potential analysis. Measure samples in nearly every possible suspension environment from high salts such as PBS and sea water to organic solvents and of course aqueous solutions. Particle and protein sizing, with the highest sensitivity, utilizing three measurement angles for truly unbiased measurement results. The NanoBrook Omni utilizes a backscattering angle as well as 90° and 15°.

Brookhaven's NanoBrook 90Plus Zeta instrument combines our NanoBrook 90Plus and NanoBrook ZetaPlus instruments into one versatile package for routine sizing and zeta potential analysis. It employs Dynamic Light Scattering (DLS) for particles/molecules size and Electrophoretic Light Scattering (ELS) for particles/molecules surface charge evaluation. This package not only allows rapid measurements of the effective size and zeta potential of samples, but also provides further information on multimode distribution in size and surface charge in polydisperse samples. Based on the proven technologies of Brookhaven, the NanoBrook 90Plus Zeta guarantees excellent mobility measurement performance in aqueous suspensions and low salt environments.

Brookhaven's NanoBrook 90Plus PALS instrument combines our NanoBrook 90Plus and NanoBrook ZetaPALS instruments in to one powerful package for sizing and zeta potential analysis. With over a decade of proven records in diverse applications, Brookhaven's pioneer Phase Analysis Light Scattering (PALS) technology remains a step ahead of the competition. This package delivers unparalleled zeta potential (surface charge) measurement sensitivity and accuracy. It also provides unique real-time (in-situ) monitoring capability for electrophoretic response of particles/molecules under an electric field, a valuable tool ONLY from Brookhaven for delicate biological entities like proteins and exosomes. It has been successfully utilized in nearly every possible suspension environment from high salts such as PBS and sea water to organic solvents and of course aqueous solutions.

For measurements of very low mobilities, the NanoBrook ZetaPALS is the answer. The only answer! With concepts developed at Bristol University and Brookhaven Instruments, the NanoBrook ZetaPALS determines zeta potential using Phase Analysis Light Scattering: A technique that is up to 1,000 times more sensitive than traditional light scattering methods based on the shifted frequency spectrum. Electrostatic repulsion of colloidal particles is often the key to understanding the stability of any dispersion. A simple, easy measurement of the electrophoretic mobility "even in nonpolar liquids" yields valuable information. Measurements made in water and other polar liquids are easy and fast with the NanoBrook ZetaPlus. Such measurements cover the range of typically ± (6 to 100) mV, corresponding to mobilities of ± 0.5-8x10-8 m 2 /V·s. The NanoBrook ZetaPALS covers this full range, of course, and extends it by a factor of 1000 in sensitivity!

The NanoBrook ZetaPlus is the simplest and most accurate particle electrophoresis system available. This revolutionary instrument has been designed to eliminate the short coming inherent in other zeta potential instruments. The ZetaPlus software is simple and intuitive to operate but yet offers flexibility and a full range of means for those that whish to tune their experiments to specific circumstances. The unique cell configuration eliminates the electroosmotic effect: No stationary levels, no alignment, and no calibration are required; as evidenced by the excellent agreement with NIST1980, a standard reference material. The NanoBrook ZetaPlus uses low cost, disposable sample cells. There is no assembly or maintenance required: Cross contamination is eliminated. Glass and quartz cells are available optionally. The same basic cell design is used with the NanoBrook 90Plus Zeta, ZetaPALS, 90Plus PALS, and Omni.

The BI-ZTU, autotitrator option for the NanoBrook zeta potential analyzers is ideal for automatic determination of the isoelectric point, the IEP, of colloidal materials. Four pumps provide unparalled flexibility for optimizing reagent use. The dramatic savings of reduced labor costs will also encourage larger scale studies that will produce more valuable results. In addition, the BI-ZTU can be used to evaluate the effect of salt concentration on zeta potential. Also, the surfactant costs can be minimized. Use the BI-ZTU to find the minimum concentration at which the zeta potential does not significantly change.

The Surface Zeta Potential feature allows the user to measure the electrical charge on materials like coated glass, plastic, tape, or other flexible surfaces. A series of measurements are taken on probe particles at different distances from a surface and the Surface Zeta Potential is calculated as shown above.

Designed to operate with NanoBrook series particle characterisation instruments, Particle Solutions software suite integrates characterisation of 5 different particle measurement technologies - DLS, SLS, Phase Analysis Light Scattering (PALS), micro-Rheology and Molecular Weight Determination in one package. The new version of this popular software suite for NanoBrook series particle characterisation instruments includes a host of useful new features. New features include Laboratory Information Management System support, Surface Zeta Potential measurement capability, Multimodal Size Distribution refinement, Health Mode post-measurement analysis, and Statistical Process Control. Safeguarding the investment of existing users - measurements made with earlier versions of the software can be imported into Particle Solutions, and then analyzed with the same powerful tools.

Note: Particle Solutions is only usable with Brookhaven Instruments light scattering systems.

The AYE Combo Refractometer /Viscometer sets a new standard for the detection of intrinsic viscosity of highly diluted samples. The Refractometer is integral part of the viscometer, therefore both concentration and viscosity are measured at exactly the same time on the very same sample segment. The AYE Combo allows a much more accurate determination of molecular parameters and is particular suited for those application focused on the structure and branching of the investigated polymer.

Within a GPC/SEC Chromatography system, a viscometer allows use of a universal calibration. Molecular weights obtained with this method are therefore independent of the polymer standards used to build the calibration and can be considered to be close to absolute values. Also, a viscometer will allow determination of further molecular parameters giving insight about the physical structure of the investigated polymer and even opening the gate to determination of branching parameters. All viscometers for GPC/SEC currently on the market, including the AYE Viscometer, base their principle on the measurement of the differential pressure across a capillary network. TESTA has been able to dramatically reduce the noise level and increase sensitivity by more than an order of magnitude compared to any viscometer available. This allows usage at much lower flow rates than it has been possible. Detection of lower molecular weight and at lower concentration are now also possible. Semi-micro applications are currently easily reached.

ParSEC is a powerful new suite of software for multi detector, macromolecular characterization and represents the most significant development in GPC/SEC analysis. ParSEC is compatible with ALL GPC/SEC systems and detectors. Many attractive and practical features have been written into the new software for the benefit of chromatographers, including "function specific" views, ensuring the uncluttered display of information relevant to the task at hand, customizable display and annotation options for all graph types, plus a Database approach for practical storage and archiving of data and results associated with any application.

GPC/SEC Chromatography is impossible without Polymer Standards. For QC Applications which mostly uses a single concentration detector, Polymer Standards are required for Calibration of the Columns which then allows calculation of Molecular Weights. More complex GPC/SEC Systems with Viscometers and MALS, require Polymer Standards for the determination of Instrument Constants and for System Validation. These are the facts which make GPC/SEC without Polymer Standards impossible. A ReadyCal™ Kit combines highest quality standards with easy and fast handling, reducing errors in sample preparation practically to zero. Three sets each of four different pre-mixed standards in 1.5 mL screw cap Vials build the strong backbone of a reliable calibration curve. Just add the desired amount of solvent, shake according to instruction and inject. Column calibration cannot be easier.

Brookhaven's NanoBrook Omni instrument combines the best technology from our particle/protein sizer and zeta potential analyzer in to one powerful and accurate solution for sizing and zeta potential analysis. Measure samples in nearly every possible suspension environment from high salts such as PBS and sea water to organic solvents and of course aqueous solutions. Particle and protein sizing, with the highest sensitivity, utilizing three measurement angles for truly unbiased measurement results. The NanoBrook Omni utilizes a backscattering angle as well as 90° and 15°.

Brookhaven's NanoBrook 173Plus instrument is the go-to-solution for characterization of proteins, antibodies, nanoparticles, macromolecular assemblies and other molecules/particles of small sizes. The NanoBrook 173Plus uses backscattering detection for the highest sensitivity and accuracy optimized for molecules and particles less than a few tens of nanometers. Detection at 90° is used for larger particles.

Brookhaven's NanoBrook 173 instrument is the go-to-solution for characterization of proteins, antibodies, nanoparticles, macromolecular assemblies and other molecules/particles of small sizes. The NanoBrook 173 uses backscattering detection for the highest sensitivity and accuracy optimized for molecules and particles less than a few tens of nanometers.

The NanoBrook 90Plus particle size analyzer incorporates all you need for fast, routine, sub-micron measurements. Based on the principles of Dynamic Light Scattering (DLS), most measurements only take a minute or two. Choose the optional avalanche photo diode (BI-APD) for weak scatters. The instrument can be upgraded later on to include zeta potential measurement. Please see the 90Plus Zeta and 90Plus PALS for instruments combining sizing and zeta potential.

The Brookhaven BI-DCP is a digitally controlled, high resolution, particle size distribution analyzer. It yields high resolution results in the size range from 0.01 to 30 microns with typical analysis times ranging from 5 to 30 minutes. The DCP softwareprovides easy instrument control, data analysis, and database management. The software is menu-driven and permits a variety of report formats.

Based on first principle, the BI-XDC is the only X-Ray disc centrifuge that measures particle size without calibration or absorption correction. The high resolution instrument can resolve peaks as close as a 15% size differential and quantify distribution accurately. Homogeneous start with scanning head makes for quick measurements.

The BI-XDC is the ideal instrument for QC, QA and research. The instrument combines gravitational and centrifugal sedimentation for Claysfast, accurate size distribution from nanometers to tens of micrometers. The scanning X-ray head speeds up measurements for a typical 8 minutes measurement. The X-ray detection gives high accuracy, no optical corrections, quantitative measurements. The BI-XDC features a reproducible digitally controlled disk speed for best performance and accuracy. Merging the centrifuge and gravity mode covers a broad size range from 0.01 to 100 microns.

Designed to operate with NanoBrook series particle characterisation instruments, Particle Solutions software suite integrates characterisation of 5 different particle measurement technologies - DLS, SLS, Phase Analysis Light Scattering (PALS), micro-Rheology and Molecular Weight Determination in one package. The new version of this popular software suite for NanoBrook series particle characterisation instruments includes a host of useful new features. New features include Laboratory Information Management System support, Surface Zeta Potential measurement capability, Multimodal Size Distribution refinement, Health Mode post-measurement analysis, and Statistical Process Control. Safeguarding the investment of existing users - measurements made with earlier versions of the software can be imported into Particle Solutions, and then analyzed with the same powerful tools.

Note: Particle Solutions is only usable with Brookhaven Instruments light scattering systems.

With a Brookhaven Instruments BI-200SM Research Goniometer System this rich field of exploration is open to you for studies of both Static Light Scattering (SLS) and Dynamic Light Scattering (DLS). The Bl-200SM Research Goniometer System provides access to all of these studies with an automatic,modular and versatile system. It is a precision instrument designed for exacting scattering measurements. Based on a special turntable with precision ball bearings and stepping motor, the Bl-200SM's modern design and quality construction guarantee precise measurements due to the wobble-free movement of the detector. It is field proven in hundreds of laboratories. It is ideal for macro-molecular studies and submicron particle sizing. The BI-200SM's modularity simplifies system expansion. Featuring a standard optical rail, the BI-200SM can be used with neutral density filters, a polarizer, an analyzer, and a reference detector. Special sample requirements can often be met by changing the cell holder design or size.

NEW - Particle Explorer Software for the 200SM Goniometer System for DLS and SLS experiments - NEW

Quickly, easily, and accurately determine absolute molecular weights of proteins and polymers. Eliminate SEC/GPC column calibration and improve data quality. Rapidly reduce uncertainty with no assumptions required and true extrapolation to zero angle. Best of all, the BI-MwA has the highest performance/price ratio of any light scattering detector used for molecular weight determination. There are two ways to use the BI-MwA: Determine the molecular weight distribution (flow mode); or determine the average molecular weight (batch-mode).

UV Detectors provide unsurpassed sensitivity and selectivity as concentration detectors in GPC/SEC. The only limitation is that the sample must contain chromophoric groups and that the solvent used provide a window in the absorption range of UV light. With these conditions fulfilled, a UV Detector is of great use as a single concentration detector in GPC/SEC or, combined with a DRI Detector, for the determination of composition distribution of copolymers. The AYE Rapid Scanning UV combines high sensitivity, a huge linear range of more that 4 orders of magnitude and fl exibility in the application, with solid physical base of clearly defined bandwidth and wavelength precision. It allows detection at two wavelengths, optional four wavelengths, at the same time and is therefore best suited for application where complex copolymers need to be characterized.

ParSEC is a powerful new suite of software for multi detector, macromolecular characterization and represents the most significant development in GPC/SEC analysis. ParSEC is compatible with ALL GPC/SEC systems and detectors. Many attractive and practical features have been written into the new software for the benefit of chromatographers, including "function specific" views, ensuring the uncluttered display of information relevant to the task at hand, customizable display and annotation options for all graph types, plus a Database approach for practical storage and archiving of data and results associated with any application.

GPC/SEC Chromatography is impossible without Polymer Standards. For QC Applications which mostly uses a single concentration detector, Polymer Standards are required for Calibration of the Columns which then allows calculation of Molecular Weights. More complex GPC/SEC Systems with Viscometers and MALS, require Polymer Standards for the determination of Instrument Constants and for System Validation. These are the facts which make GPC/SEC without Polymer Standards impossible. A ReadyCal™ Kit combines highest quality standards with easy and fast handling, reducing errors in sample preparation practically to zero. Three sets each of four different pre-mixed standards in 1.5 mL screw cap Vials build the strong backbone of a reliable calibration curve. Just add the desired amount of solvent, shake according to instruction and inject. Column calibration cannot be easier.

Quickly, easily, and accurately determine absolute molecular weights of proteins and polymers. Eliminate SEC/GPC column calibration and improve data quality. Rapidly reduce uncertainty with no assumptions required and true extrapolation to zero angle. Best of all, the BI-MwA has the highest performance/price ratio of any light scattering detector used for molecular weight determination.

GPC/SEC Chromatography with MALS Detector is a very powerful tool capable of delivering absolute values of the compound under investigation. To achieve this, it is absolutely necessary to obtain concentration data along with the molar mass. In this scenario, a common DRI will lack the capability to deliver data measured at the same wavelength as the laser used in the MALS Detector. This fact will introduce a non-neglectable error in all calculations performed, thus questioning the obtained results. The AYE DRI operates at the very same wavelength your MALS Detector does, thus improving reliability of your results.

ParSEC is a powerful new suite of software for multi detector, macromolecular characterization and represents the most significant development in GPC/SEC analysis. ParSEC is compatible with ALL GPC/SEC systems and detectors. Many attractive and practical features have been written into the new software for the benefit of chromatographers, including "function specific" views, ensuring the uncluttered display of information relevant to the task at hand, customizable display and annotation options for all graph types, plus a Database approach for practical storage and archiving of data and results associated with any application.

GPC/SEC Chromatography is impossible without Polymer Standards. For QC Applications which mostly uses a single concentration detector, Polymer Standards are required for Calibration of the Columns which then allows calculation of Molecular Weights. More complex GPC/SEC Systems with Viscometers and MALS, require Polymer Standards for the determination of Instrument Constants and for System Validation. These are the facts which make GPC/SEC without Polymer Standards impossible. A ReadyCal™ Kit combines highest quality standards with easy and fast handling, reducing errors in sample preparation practically to zero. Three sets each of four different pre-mixed standards in 1.5 mL screw cap Vials build the strong backbone of a reliable calibration curve. Just add the desired amount of solvent, shake according to instruction and inject. Column calibration cannot be easier.

GPC/SEC Chromatography with MALS Detector is a very powerful tool capable of delivering absolute values of the compound under investigation. To achieve this, it is absolutely necessary to obtain concentration data along with the molar mass. In this scenario, a common DRI will lack the capability to deliver data measured at the same wavelength as the laser used in the MALS Detector. This fact will introduce a non-neglectable error in all calculations performed, thus questioning the obtained results. The AYE DRI operates at the very same wavelength your MALS Detector does, thus improving reliability of your results.

Quickly, easily, and accurately determine absolute molecular weights of proteins and polymers. Eliminate SEC/GPC column calibration and improve data quality. Rapidly reduce uncertainty with no assumptions required and true extrapolation to zero angle. Best of all, the BI-MwA has the highest performance/price ratio of any light scattering detector used for molecular weight determination.

ParSEC is a powerful new suite of software for multi detector, macromolecular characterization and represents the most significant development in GPC/SEC analysis. ParSEC is compatible with ALL GPC/SEC systems and detectors. Many attractive and practical features have been written into the new software for the benefit of chromatographers, including "function specific" views, ensuring the uncluttered display of information relevant to the task at hand, customizable display and annotation options for all graph types, plus a Database approach for practical storage and archiving of data and results associated with any application.

GPC/SEC Chromatography is impossible without Polymer Standards. For QC Applications which mostly uses a single concentration detector, Polymer Standards are required for Calibration of the Columns which then allows calculation of Molecular Weights. More complex GPC/SEC Systems with Viscometers and MALS, require Polymer Standards for the determination of Instrument Constants and for System Validation. These are the facts which make GPC/SEC without Polymer Standards impossible. A ReadyCal™ Kit combines highest quality standards with easy and fast handling, reducing errors in sample preparation practically to zero. Three sets each of four different pre-mixed standards in 1.5 mL screw cap Vials build the strong backbone of a reliable calibration curve. Just add the desired amount of solvent, shake according to instruction and inject. Column calibration cannot be easier.

The specific refractive index increment (dn/dc) is one of the values required for the determination of absolute molecular weight with Static Light Scattering (SLS). The importance of this parameter becomes clear when observing the composition of the Debye Constant used for calculations, where the dn/dc is a squared term. As such, a relatively small error in dn/dc will lead to twice the error in molecular weight. It is important to notice that the dn/dc value must be obtained at the same wavelength as the Laser used for Light Scattering or a further unknown error will be introduced. Determination of the specifi c refractive index (dn/dc) of any dissolved sample can be easily achieved in batch mode with the AYE dn/dc Refractometer, with just a few syringes needed. Measurement of a set of concentrations of the sample under investigation with the AYE dn/dc Refractometer will lead to reliable and reproducible results within minutes. A huge number of wavelength options are available to perfectly match the Laser used in SLS, making sure your results will be perfect.

Quickly, easily, and accurately determine absolute molecular weights of proteins and polymers. Eliminate SEC/GPC column calibration and improve data quality. Rapidly reduce uncertainty with no assumptions required and true extrapolation to zero angle. Best of all, the BI-MwA has the highest performance/price ratio of any light scattering detector used for molecular weight determination. There are two ways to use the BI-MwA: Determine the molecular weight distribution (flow mode); or determine the average molecular weight (batch-mode).